Christophe Legendre Selected Research

Alternative Pathway Complement C3 Convertase

11/2017

C5 nephritic factors drive the biological phenotype of C3 glomerulopathies.

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Christophe Legendre Research Topics

Disease

25	Infections 01/2022 - 10/2002
25	Neoplasms (Cancer) 01/2021 - 11/2006
23	Proteinuria 01/2021 - 04/2003
18	Chronic Kidney Failure (Chronic Renal Failure) 11/2021 - 05/2002
13	Fibrosis (Cirrhosis) 07/2018 - 12/2007
11	Inflammation (Inflammations) 11/2021 - 12/2009
10	Chronic Renal Insufficiency 01/2022 - 06/2009
10	Delayed Graft Function 08/2016 - 05/2002
8	Renal Insufficiency (Renal Failure) 01/2020 - 04/2003
7	Focal Segmental Glomerulosclerosis (Glomerulosclerosis, Focal) 01/2021 - 08/2004
6	Hypertension (High Blood Pressure) 01/2020 - 02/2003
6	Nephrotic Syndrome (Syndrome, Nephrotic) 10/2019 - 04/2005
6	Atrophy 01/2018 - 08/2008
5	Kidney Diseases (Kidney Disease) 01/2022 - 08/2012
5	Melanoma (Melanoma, Malignant) 11/2021 - 01/2017
5	Membranous Glomerulonephritis (Membranous Nephropathy) 07/2021 - 08/2012
5	Lymphoproliferative Disorders (Lymphoproliferative Disorder) 06/2021 - 11/2010
5	Anemia 01/2014 - 07/2003
4	COVID-19 12/2021 - 12/2020
4	Diarrhea 10/2021 - 07/2011
4	Acute Kidney Injury (Acute Renal Failure) 02/2021 - 09/2008
4	Viremia 12/2020 - 07/2002
3	Virus Diseases (Viral Diseases) 01/2021 - 03/2013
3	Obesity 01/2021 - 01/2015
3	Neoplasm Metastasis (Metastasis) 11/2020 - 11/2017
3	Vasculitis (Vasculitides) 10/2020 - 05/2011
3	Cystinosis 01/2020 - 01/2012
3	Hyperglycemia 01/2020 - 08/2009
3	Atypical Hemolytic Uremic Syndrome 12/2019 - 07/2013
3	Glomerulonephritis 10/2019 - 08/2012
3	Thrombosis (Thrombus) 04/2018 - 03/2012
3	Opportunistic Infections (Opportunistic Infection) 01/2017 - 10/2002
3	Antiphospholipid Syndrome (Antiphospholipid Antibody Syndrome) 01/2017 - 03/2012
3	Cardiovascular Diseases (Cardiovascular Disease) 08/2016 - 01/2012
3	Segmental glomerulosclerosis 02/2016 - 04/2010
3	Wounds and Injuries (Trauma) 08/2013 - 01/2009
3	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 02/2010 - 05/2002
2	IGA Glomerulonephritis (IGA Nephropathy) 01/2022 - 08/2012
2	Pyelonephritis 01/2022 - 01/2017
2	Ischemia 11/2021 - 01/2010
2	Ulcer 06/2021 - 11/2013
2	Rare Diseases (Rare Disease) 01/2021 - 12/2017
2	Late Onset Disorders 01/2021 - 03/2008
2	Lymphopenia (Lymphocytopenia) 01/2021 - 03/2016
2	Kaposi Sarcoma (Kaposi's Sarcoma) 08/2019 - 10/2008
2	Hepatocellular Carcinoma (Hepatoma) 12/2017 - 07/2012
2	Non-alcoholic Fatty Liver Disease 12/2017 - 09/2015
2	Membranoproliferative Glomerulonephritis (Membranoproliferative Glomerulonephritis, Type II) 11/2017 - 08/2012
2	Carcinoma (Carcinomatosis) 04/2017 - 01/2007
2	Skin Neoplasms (Skin Cancer) 04/2017 - 08/2010
2	Cryptosporidiosis 01/2017 - 10/2014
2	Necrosis 01/2017 - 08/2014
2	Arteriosclerosis 08/2015 - 05/2011
2	Diabetes Mellitus 07/2015 - 01/2015

Drug/Important Bio-Agent (IBA)

17	AntibodiesIBA 06/2021 - 01/2009
12	CreatinineIBA 01/2021 - 02/2003
12	Sirolimus (Rapamycin)FDA Link 01/2019 - 09/2003
11	Calcineurin InhibitorsIBA 01/2019 - 11/2005
9	Biological ProductsIBA 01/2022 - 01/2013
8	RNA (Ribonucleic Acid)IBA 01/2018 - 01/2012
7	DNA (Deoxyribonucleic Acid)IBA 10/2019 - 07/2002
7	SteroidsIBA 01/2016 - 04/2005
7	Cyclosporine (Ciclosporin)FDA LinkGeneric 01/2012 - 04/2005
6	Abatacept (Orencia)FDA Link 12/2021 - 11/2010
6	Complement System Proteins (Complement)IBA 12/2019 - 07/2013
6	Mycophenolic Acid (Cellcept)FDA LinkGeneric 05/2019 - 07/2003
5	Biomarkers (Surrogate Marker)IBA 11/2021 - 08/2008
5	MTOR InhibitorsIBA 10/2019 - 11/2006
5	Everolimus FDA Link 10/2019 - 07/2009
5	TOR Serine-Threonine KinasesIBA 08/2019 - 11/2010
5	Tacrolimus (Prograf)FDA LinkGeneric 05/2019 - 12/2005
5	Immunoglobulin G (IgG)IBA 05/2017 - 07/2014
4	Hemoglobins (Hemoglobin)IBA 01/2022 - 01/2004
4	Antiviral Agents (Antivirals)IBA 04/2018 - 10/2002
4	Valacyclovir (Valtrex)FDA LinkGeneric 05/2006 - 10/2002
3	Monoclonal AntibodiesIBA 01/2022 - 02/2010
3	Anti-Bacterial Agents (Antibiotics)IBA 01/2022 - 08/2013
3	Pharmaceutical PreparationsIBA 01/2021 - 06/2015
3	Cystine (L-Cystine)IBA 01/2020 - 01/2012
3	eculizumab FDA Link 12/2017 - 07/2013
3	Intravenous Immunoglobulins (IVIG)FDA Link 11/2016 - 09/2008
3	HLA Antigens (Human Leukocyte Antigens)IBA 06/2015 - 05/2014
2	C-Reactive ProteinIBA 01/2022 - 09/2020
2	HLA-D AntigensIBA 07/2021 - 01/2021
2	Protein Isoforms (Isoforms)IBA 01/2021 - 01/2018
2	ChemokinesIBA 12/2020 - 12/2017
2	Cysteamine (Mercaptamine)FDA Link 01/2020 - 01/2012
2	MicroRNAs (MicroRNA)IBA 10/2019 - 09/2015
2	Transforming Growth Factor beta (TGF-beta)IBA 12/2017 - 09/2015
2	Insulin (Novolin)FDA Link 12/2017 - 08/2009
2	Azathioprine (Imuran)FDA LinkGeneric 04/2017 - 07/2003
2	Antiphospholipid AntibodiesIBA 01/2017 - 07/2014
2	EnzymesIBA 12/2016 - 01/2004

Therapy/Procedure

64	Kidney Transplantation 01/2022 - 01/2002
60	Transplantation 01/2022 - 05/2002
31	Therapeutics 01/2022 - 10/2002
8	Organ Transplantation 11/2021 - 03/2008
3	Nephrectomy 01/2022 - 07/2012
2	Renal Replacement Therapy (Therapies, Renal Replacement) 02/2021 - 06/2015
2	Aftercare (After-Treatment) 01/2018 - 01/2016